Mezzotint engraving by Thomas Burke of 'IOHANNES HENRIVS HAMPE', i.e.the German-born Fellow of the Royal Society Johann Heinrich Hampe, from a painting by Angelica Kaufman, with twenty-seven line Latin inscription.

On one side of a piece of paper, roughly 28 x 21.5 cm. On aged and worn paper. The engraving, roughly 11 x 13 cm, placed at the head of the page, is a head and shoulders portrait of Hampe, depicted in an oval frame, with inscription in Greek wound round a staff with snake (recalling the rod of Asclepius) and laurel sprig. Kauffmann's name engraved at bottom left and Burke's at bottom right. Beneath the engraving is a 27-line inscription beginning: “IOHANNES HENRICVS HAMPE | SIEGENA-NASSOVICVS | MEDICINAE DOCTOR DVISBVRGENSIS CLIVORVM'. Hampe pursued the Philosopher's stone at the expense of health and money.