Autograph Signature on fragment of letter.

Victorian phrenologist (1788-1858) and natural philosopher. Paper dimensions roughly four and a half inches by two and a quarter. Very good. From autograph album. Mounted on larger piece of lilac paper. Crease line affecting first line of text. Reads 'I am | My dear Major Mair | Very truly yours | Geo. Combe'. Docketed in pencil at foot by Dame Sarah Elizabeth Siddons Mair (died 1941) '(Phrenologist) | Written to my Father - S. E. S. M.'